Cette patiente de 52 ans, G2P2, n’est pas tabagique et ne présente pas de métrorragies. Elle a subi une imprégnation Distilbène in utéro. L’indication du Distilbène (DES) dans la prévention des FCS précoces et le traitement des métrorragies du 1er trimestre correspondait à la période d’embryogénèse très sensible aux agents exogènes. Surtout prescrit entre 1965…
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